Clinical Psychology | Developmental Neuroscience
I study how neurobiological development influences mental and physical health trajectories. I am particularly interested in understanding how sensitive periods of neurobiological development create both vulnerabilities to environmental adversity as well as opportunities for prevention and intervention. To do so, I take an interdisciplinary approach across neural, hormonal, microbial, and psychosocial indices to assess the emergence of mental health symptoms and health-risk behaviors during adolescence.
Recent News and Updates
Our paper made Oregon State's Year in Science No2 spot!
I joined the FLUX Trainee Committee!
I joined the University of Washington Clinical Psychology Internship as part of the Child Track in July 2019!
I successfully defended my dissertation in May 2019! You can check it out at the link above!
Check Out my TedX talk "Teen Behavior: What's The Gut Got to Do With It?" !
Developmental Social & Affective Neuroscience
How does social and affective brain function and functional connectivity influence
mental health and health-risk behavior during adolescence?
I study these questions using task-based functional magnetic resonance imaging (fMRI) and resting state functional connectivity MRI.
Taxonomic & Functional Gut Microbiome
How do the bacteria and functional capacity of these microbes in our large intestines influence our
mood and brain function during development?
I study these questions using 16sr RNA microbial sequencing to identify "who is there" and shotgun metagenomics to identify "what they are doing."
How do social and cultural environments influence the development of mental health and health risk behaviors,
such as depression and risk-taking behaviors?
How can these psychosocial environments alter the trajectory of developing neurobiology, including brain, neuroendocrine, and microbiome function -- for better or for worse?
I study these questions by studying children with a history of foster care or child welfare involvement. More recently, I have extended these questions to see how a range of early and chronic childhood adversity, including poor economic and social environments can influence the trajectory of behavioral and neurobiological development.
Previously, I worked under Dr. Nim Tottenham at the University of California Los Angeles (UCLA) to study social and emotional brain and hormonal development of children that had been institutionalized abroad and are now adopted in the USA.
My clinical training focuses on parent training, pediatric neuropsychology, psychological assessments, and adolescent depression. I completed my psychology residency at Seattle Children's Hospital / University of Washington's School of Medicine. There my training included a broad range of child and adolescent psychiatric and medical disorders in the context of outpatient neuropsychological assessments, outpatient child therapy and parent management training, as well as inpatient child psychiatry behavioral medical unit therapy and inpatient psychology consult & liaison. Previously, I primarily used neuropsychological assessments with children and adolescents displaying complex social, cognitive, and medical life histories, as well as mild traumatic brain injuries. My theoretical orientation integrates cognitive behavioral and biopsychosocial approaches.
Pediatric Neuropsychology & Psychological Assessment
I trained in general pediatric psychological evaluations and in pediatric neuropsychological evaluations with children 4-18 years old in an outpatient clinic. Training occurred in the context of a multidisciplinary team, including a psychologist, social worker, speech language pathologist, occupational therapist, and developmental pediatrician. Neuropsychological evaluations occurred in the context of a multidisciplinary team and full-day single team evaluations.
Social Learning & Behaviorally-Based Interventions
I trained in a community mental health agency, as part of the Early Intervention Foster Care (EIFC) team. I was specifically trained in the intervention, Multidimensional Treatment Foster Care- Preschool (MTFC-P). Theoretical orientation was centered in social learning and behavioral theory and Parent Management Training Oregon (PMTO). I worked as an individual child therapist and group therapy leader for children 3-8 years old.
I was trained and served as an intervention coach for the strength-based parenting intervention for parents of low socioeconomic status, led by Dr. Philip Fisher, Filming Interactions to Nurture Development (FIND). I additionally served as an intervention coach for a pilot parenting intervention for depressed mothers of adolescents, led by Dr. Nicholas Allen and Dr. Lisa Sheeber.
Pediatric diagnostic training include, but not limited to:
Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS)
Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS)
Additional training include, but not limited to:
Trauma Focused Cognitive Behavioral Therapy (TF-CBT) - online course
Incredible Years (IY), parent behavioral management training (PBMT)
Collaborative Assessment & Management of Suicidality (CAMS) Training Certificates in:
Cognitive Behavioral Therapy
I trained in Cognitive Behavioral Therapy (CBT). This included individual therapy with adults 18- 25 years old for anxiety and mood-related disorders.
Adult diagnostic training including:
Structural Clinical Interview for DSM IV, V (SCID I).
I trained in Mindfulness-Based Cognitive Therapy (MBCT) and Mindfulness Based Stress Reduction (MBSR). This included group therapy with adults 18-70 years old.
Note: *denotes shared first authorship
VanTieghem, M., Korom, M., Flannery, J., Choy, T., Caldera, C., Humphreys, K., Gabard-Durnam, L.J, Goff, B., Gee, D., Telzer, E., Shapiro, M., Louie, J.Y, Fareri, D., Bolger, N., Tottenham, N. (in press). Longitudinal changes in amygdala, hippocampus and cortisol development following early caregiving adversity. Developmental Cognitive Neuroscience.
Vijayakumar, N., Shirtcliff, E., Byrne, M., Mills, K., Cheng, T., Mobasser, A., Flannery, J., Nelson, B., Flournoy, J., Wang, W., Allen, N., Pfeifer, J. (2020). Pubertal hormones and brain structure: Exploring the value of hair assays. Psychoneuroendocrinology 119:105037
Nelson, B., Pettitt, A. K., Flannery, J., & Allen, N. (2020). Psychological and Epidemiological Predictors of COVID-19 Concern and Health-Related Behaviors. PLoS One, 15(11):e0241990. PMID: 33175882 PMCID: PMC7657530
Andrews, J., Mills, K., Flournoy, J., Flannery, J., Mobasser, A., Ross, G., Durnin, M., Peake, S., Fisher, P., Pfeifer, J. (2020). Rethinking adolescent risk-taking: Perception of social risk impacts expected involvement in health-risk behaviour during adolescence. Journal of Research on Adolescence, (4):1008-1024. PMID: 32910510
Flournoy, J., Vijayakumar, N., Cheng, T., Cosme, D., Flannery, J., Vijayakumar, N., Pfeifer, J., (2020). Improving Practices and Inferences in Developmental Cognitive Neuroscience. Developmental Cognitive Neuroscience, 45:100807. PMID: 32759026 PMCID: PMC7403881
Flannery J*, Stagaman K*, Burns AR, Hickey RJ, Roos LE, Giuliano RJ, Fisher PA, Sharpton TJ (2020). Gut feelings begin in childhood: the gut metagenome correlates with early environment, caregiving, and behavior. mBio, 11(1):e02780-19. PMID: 31964729 PMCID: PMC6974564
Cheng, T*., Vijayakumar, N*., Flournoy, J., Op de Macks, Z., Peake, S., Flannery, J., Mobasser A, Alberti, S., Fisher, P., Pfeifer, J. (2020). Feeling left out or just surprised? Neural correlates of social exclusion and expectancy violations in adolescence. Cognitive, Affective, & Behavioral Neuroscience, (2):340-355. PMID: 32056138 PMCID: PMC7338003
Barendse, M., Vijayakumar, N., Byrne, M., Flannery, J., Cheng, T., Flournoy, J., Nelson, B., Cosme, D., Mobasser, A., Chavez, S., Hval, L., Brady, B., Nadel, H., Helzer, A., Shirtcliff, E., Nick Allen, N., Pfeifer J. (2020) Study protocol: Transitions in Adolescent Girls (TAG). Frontiers in Psychiatry, 10:1018. PMID: 32116825 PMCID: PMC7010724
Vijayakumar, N., Flournoy, J., Mills, K., Cheng, T., Mobasser, A., Flannery, J., Allen, N., Pfeifer J., Getting to know me better: (2020). An fMRI study of intimate and superficial self-disclosure to friends during adolescence. Journal of Personality and Social Psychology, (5):885-899. PMID: 32039615 PMCID: PMC7338033
Callaghan, B., Fields, A., Gee, D.G., Gabard-Durnam, L., Caldera, C., Humphreys, K., Goff, B., Flannery, J., Telzer, E., Shapiro, M., Tottenham, N. (2020). Mind and gut: associations between mood and gastrointestinal distress in children exposed to adversity. Development and Psychopathology, (1):309-328. PMID: 30919798 PMCID: PMC6765443
Humphreys, K., Gabard-Durnam, L., Goff, B., Telzer, E., Flannery, J., Gee, D., Park, V., Lee, S., Tottenham, N. (2019) Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology, (4):1477-1487. PMID: 30588896 PMCID: PMC6597328
Tottenham, N., Shapiro, M., Flannery, J., Caldera, C., & Sullivan, R.M. (2019). Parental presence switches avoidance to attraction learning in children. Nature Human Behaviour, (10):1070-1077. PMID: 31332302 PMCID: PMC7218758
Flannery, J., Callaghan, B., Sharpton, T., Fisher, P., Pfeifer, J., (2019). Is adolescence the missing developmental link in gut-brain axis communication? Developmental Psychobiology, (5):783-795. PMID: 30690712 PMCID: PMC6776431
Alba, L., Flannery, J., Shapiro, M., & Tottenham, N. (2019). Working Memory Moderates the Association Between Early Institutional Care and Separation Anxiety Symptoms in Late Childhood and Adolescence. Development and Psychopathology, (3):989-997. PMID: 31038094 PMCID: PMC6620150
Callaghan, B., Gee, D., Gabard-Durnam, L.J., Telzer, E., Humphreys, K., Goff, B., Shapiro, M., Flannery, J., Lumian, D., Fareri, D., Caldera, C., Tottenham, N. (2019). Decreased amygdala reactivity to parent cues protects against anxiety following early adversity: an examination across 3 years. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(7):664-671. PMID: 30952600 PMCID: PMC6612442
Op de Macks, Z*., Flannery, J.*, Peake, S., Flournoy, J., Mobasser A, Alberti, S., Fisher, P., Pfeifer, J., (2018) Novel insights from the Yellow Light Game: Safe and risky decisions differentially impact adolescent outcome-related brain function. Neuroimage, 181:568-581. PMID: 29940284 PMCID: PMC6777552
Horn, SR, Roos, LE, Beauchamp, KG, Flannery, JE, & Fisher, PA. (2018). Polyvictimization and externalizing symptoms in foster care children: the moderating role of executive function. Journal of Trauma & Dissociation, 9(3):307-324. PMID: 29547079 PMCID: PMC6774668
Roos, L., Beauchamp, K., Flannery, J., & Fisher, P. (2018). Cultural contributions to executive function. Journal of Cognition and Culture.
Flannery, J., Gabard-Durnam, L., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D., Telzer, E., Humphreys, K Lumian, D., & Tottenham, N. (2017). Diurnal cortisol after early institutional care - age matters. Developmental Cognitive Neuroscience, 25:160-166. PMID: 28442223 PMCID: PMC5520669
Flannery, J., Giuliani, N., Flournoy, J., Pfeifer, J. (2017). Neurodevelopmental changes across adolescence in viewing and labeling dynamic peer emotions. Developmental Cognitive Neuroscience, 25:113-127. PMID: 28262423 PMCID: PMC5764159
Fareri D., Laurel Gabard-Durnam. L., Goff, B., Flannery, J., Gee., B., Lumian, D., Caldera, C., & Tottenham, N. (2017). Altered ventral striatal-medial prefrontal cortex resting-state connectivity mediates adolescent social problems after early institutional care. Development and Psychopathology, 29(5):1865-1876. PMID: 29162189 PMCID: PMC5957481
Vantieghem, MR., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, KL Telzer, EH., Caldera, C., Louie, JY., Shapiro, M., Bolger, N., Tottenham, N. (2017) Positive valence bias and parent-child relationship security moderate the association between early institutional caregiving and internalizing symptoms. Development and psychopathology, 29(2): 519–533. PMCID: PMC5937229 PMID: 28401841
Flannery, J.E., Beauchamp, K.G., & Fisher, P.A. (2017). The role of social buffering on chronic disruptions in quality of care: evidence from caregiver-based interventions in foster children. Social Neuroscience, 12(1), 86-91. PMID: 27021231 PMCID: PMC5372832
Silvers, J.A., Lumian, D.S., Gabard-Durnam, L., Gee, D.G., Goff, B., Fareri, D.S., Caldera, C., Flannery, J., Telzer, E., Humphreys, K., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala–hippocampal–PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36(24), 6420-6430. PMID: 27307231 PMCID: PMC5015779
Gabard-Durnam, L.J., Gee, D. G., Goff, B., Flannery, J., Telzer, E., Humphreys, K.L., Lumian, D., Fareri, D., Caldera, C., & Tottenham N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36(17), 4771-4784. PMID: 27122035 PMCID: PMC4846673
Green, S.A., Goff, G., Gee, D.G., Gabard-Durnam, L., Flannery, J., Telzer, E.H., Humphreys, K., Louie, J., & Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry, 57(10), 1135-1144. PMID: 27260337 PMCID: PMC5030125
Fisher, P.A., Beauchamp, K.G., Roos, L.E., Noll, L.K., Flannery, J., & Delker, B.C. (2016). The Neurobiology of Intervention and Prevention in Early Adversity. Annual Review of Clinical Psychology, 12, 331-357. PMID: 26666968
Humphreys, K.L., Telzer, E.H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D.G., Lee, S.S., & Tottenham, N. (2015). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16(1), 101. PMID: 26389647 PMCID: PMC4718882
Fareri D.S., Gabard-Durnam., L, Goff B., Flannery J., Gee D.G., Lumian D.S., Caldera C., & Tottenham N. (2015). Normative development of ventral striatal resting state connectivity in humans. Neuroimage, 118, 422-437. PMID: 26087377 PMCID: PMC5553607
Telzer, E.H., Flannery, J., Humphreys, K.L., Goff, B., Gabard-Durman, L., Gee, D.G., & Tottenham, N. (2015). “The Cooties Effect”: Amygdala reactivity to opposite- versus same-sex faces declines from childhood to adolescence. Journal of Cognitive Neuroscience, 7(9):1685-96. PMID:25848681 PMCID: PMC5723398
Humphreys, K.L., Lee, S.S., Telzer, E.H., Gabard‐Durnam, L.J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration—Exploitation strategy is dependent on early experience. Developmental Psychobiology, 57(3), 313-321. PMID: 25783033 PMCID: PMC5934758
Gee*, D., Gabard-Durnam*, L., Telzer, E., Humphreys, K., Goff, B., Shapiro, M., Flannery, J., Lumian, D., Fareri, D., Caldera, C., & Tottenham, N. (2014). Maternal buffering of human amygdala–prefrontal circuitry during childhood but not adolescence. Psychological Science, 25(11): 2067–2078. PMID: 25280904 PMCID: PMC4377225
Gabard-Durnam, L., Flannery, J., Goff, B., Gee, D., Humphreys, K., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23years: A cross-sectional study. Neuroimage, 95, 193-207. PMID: 24662579 PMCID: PMC4305511
Gee, D., Gabard-Durnam, L., Flannery, J., Goff, B., Humphreys, K., Telzer, E., Hare, T., Bookheimer, S., & Tottenham, N. (2013). Early developmental emergence of human amygdala–prefrontal connectivity after maternal deprivation. Proceedings of the National Academy of Sciences, 110(39), 15638-15643. PMID: 24019460 PMCID: PMC3785723
Goff, B., Gee, D.G., Telzer, E.H., Humphreys, K.L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. PMID: 23262241 PMCID: PMC3646076
Gee, D., Humphreys, K., Flannery, J., Goff, B., Telzer, E., Shapiro, M., Bookheimer, S., & Tottenham N. (2013). A developmental shift from positive to negative connectivity in human amygdala–prefrontal circuitry. Journal of Neuroscience, 33(10), 4584-4593. PMID: 23467374 PMCID: PMC3670947
Telzer, E.H., Flannery, J., Shapiro, M., Humphreys, K., Goff, B., Gabard-Durman, L., Gee, D.G., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: an international adoption design. Journal of Neuroscience, 33(33), 13484-13488. PMID: 23946406 PMCID: PMC3742934
Olsavsky, A.K., Telzer, E.H., Shapiro, M., Humphreys, K.L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biological Psychiatry, 74(11), 853-860.PMID: 23810622 PMCID: PMC3818506
Tottenham, N., Phuong, J., Flannery, J., Gabard-Durnam, L., & Goff, B. (2013). A negativity bias for ambiguous facial-expression valence during childhood: Converging evidence from behavior and facial corrugator muscle responses. Emotion, 13(1), 92.
PMID: 22906084 PMCID: PMC4006094
Roos, L., Beauchamp, K., Flannery, J., Horn, S., Fisher, P., (2018) Interventions, Stress During Development, and Psychosocial Environment. International Handbook of Social Neuroendocrinology
updated Jan 2021